Ontology highlight
ABSTRACT:
SUBMITTER: Tian X
PROVIDER: S-EPMC5412418 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Tian Xiuzhi X Wang Feng F Zhang Lu L He Changjiu C Ji Pengyun P Wang Jing J Zhang Zhenzhen Z Lv Dongying D Abulizi Wusiman W Wang Xuguang X Lian Zhengxing Z Liu Guoshi G
International journal of molecular sciences 20170417 4
(1) Background: The binding sites of melatonin, as a multifunctional molecule, have been identified in human, porcine, and bovine samples. However, the binding sites and mechanisms of melatonin have not been reported in sheep; (2) Methods: Cumulus-oocyte complexes (COCs) were cultured in TCM-199 supplemented with melatonin at concentrations of 0, 10<sup>-3</sup>, 10<sup>-5</sup>, 10<sup>-7</sup>, 10<sup>-9</sup>, and 10<sup>-11</sup> M. Melatonin receptors (MT1 and MT2) were evaluated via immuno ...[more]