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Wearable smart sensor systems integrated on soft contact lenses for wireless ocular diagnostics.


ABSTRACT: Wearable contact lenses which can monitor physiological parameters have attracted substantial interests due to the capability of direct detection of biomarkers contained in body fluids. However, previously reported contact lens sensors can only monitor a single analyte at a time. Furthermore, such ocular contact lenses generally obstruct the field of vision of the subject. Here, we developed a multifunctional contact lens sensor that alleviates some of these limitations since it was developed on an actual ocular contact lens. It was also designed to monitor glucose within tears, as well as intraocular pressure using the resistance and capacitance of the electronic device. Furthermore, in-vivo and in-vitro tests using a live rabbit and bovine eyeball demonstrated its reliable operation. Our developed contact lens sensor can measure the glucose level in tear fluid and intraocular pressure simultaneously but yet independently based on different electrical responses.

SUBMITTER: Kim J 

PROVIDER: S-EPMC5414034 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature

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Wearable smart sensor systems integrated on soft contact lenses for wireless ocular diagnostics.

Kim Joohee J   Kim Minji M   Lee Mi-Sun MS   Kim Kukjoo K   Ji Sangyoon S   Kim Yun-Tae YT   Park Jihun J   Na Kyungmin K   Bae Kwi-Hyun KH   Kyun Kim Hong H   Bien Franklin F   Young Lee Chang C   Park Jang-Ung JU  

Nature communications 20170427


Wearable contact lenses which can monitor physiological parameters have attracted substantial interests due to the capability of direct detection of biomarkers contained in body fluids. However, previously reported contact lens sensors can only monitor a single analyte at a time. Furthermore, such ocular contact lenses generally obstruct the field of vision of the subject. Here, we developed a multifunctional contact lens sensor that alleviates some of these limitations since it was developed on  ...[more]

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