Detection and comparison of microRNAs in the caprine mammary gland tissues of colostrum and common milk stages.
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ABSTRACT: Background
MicroRNAs (miRNAs) have a great influence on various physiological functions. A lot of high-throughput sequencing (HTS) research on miRNAs has been executed in the caprine mammary gland at different lactation periods (common milk lactation and dry period), but little is known about differentially expressed miRNAs in the caprine mammary gland of colostrum and peak lactation periods.Result
This study identified 131 differentially expressed miRNAs (P?2 colostrum normalized expression (NE)/peak lactation NE?>?1 or log2 colostrum NE/peak lactation NE?2 colostrum NE/peak lactation NE?>?1 or log2 colostrum NE/peak lactation NE?ConclusionsOur finding suggested that the profiles of miRNAs were related to the physiological functions of mammary gland in the colostrum and peak lactation periods. The biological features of these miRNAs may help to clarify the molecular mechanisms of lactation and the development of caprine mammary gland.
SUBMITTER: Hou J
PROVIDER: S-EPMC5414302 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Publications
Detection and comparison of microRNAs in the caprine mammary gland tissues of colostrum and common milk stages.
Hou Jinxing J An Xiaopeng X Song Yuxuan Y Cao Binyun B Yang Heping H Zhang Zhou Z Shen Wenzheng W Li Yunpu Y
BMC genetics 20170502 1
<h4>Background</h4>MicroRNAs (miRNAs) have a great influence on various physiological functions. A lot of high-throughput sequencing (HTS) research on miRNAs has been executed in the caprine mammary gland at different lactation periods (common milk lactation and dry period), but little is known about differentially expressed miRNAs in the caprine mammary gland of colostrum and peak lactation periods.<h4>Result</h4>This study identified 131 differentially expressed miRNAs (P < 0.05 and log<sub>2< ...[more]
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