Vitamin Pharmacogenomics: New Insight into Individual Differences in Diseases and Drug Responses.
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ABSTRACT:
SUBMITTER: He HY
PROVIDER: S-EPMC5414710 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Publications
Vitamin Pharmacogenomics: New Insight into Individual Differences in Diseases and Drug Responses.
He Hai-Yan HY Liu Mou-Ze MZ Zhang Yue-Li YL Zhang Wei W
Genomics, proteomics & bioinformatics 20170401 2
Vitamins are vital to sustain normal physiological function, metabolism, and growth for all living organisms. Being an integral component of coenzyme, vitamins can affect the catalytic activities of many enzymes and the expression of drug transporters. Genetic variations in metabolism and/or transporter genes of drugs can influence the exposure of the human body to drugs and/or their active metabolites, thus contributing to the variations in drug responses and toxicities. Nonetheless, pharmacoge ...[more]
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