Dataset Information

Skin needling as a treatment for acne scarring: An up-to-date review of the literature.

ABSTRACT:

Background

Skin needling is a technique used to improve the appearance of acne scarring.

Objective

To comprehensively review the medical literature regarding skin needling as a treatment for acne scarring.

Methods

A literature search was performed using the PubMed, Medline, and Embase databases, in addition to reviewing the bibliographies of relevant articles.

Results

Ten studies presented patients treated with skin needling alone, while eight studies discussed skin needling in combination with other treatments for acne scarring. All studies showed improvements in scarring after needling, with 12 reporting statistical significance. The median number of treatments when needling was used alone was three, the median duration between treatments was 4 weeks, and the median needle length used was 1.5 mm. Reported adverse events were infrequent and included post-inflammatory hyperpigmentation, "tram track" scarring, acne, and milia. There were no reports of bacterial infections.

Limitations

The studies reviewed were heterogeneous in design and of variable validity, with some not reporting statistical significance.

Conclusion

There is moderate evidence to suggest that skin needling is beneficial and safe for the treatment of acne scarring. However, double-blinded, randomized controlled trials are required to make more definitive conclusions.

SUBMITTER: Harris AG

PROVIDER: S-EPMC5418754 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature

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Publications

Skin needling as a treatment for acne scarring: An up-to-date review of the literature.

Harris Adam G AG Naidoo Catherine C Murrell Dedee F DF

International journal of women's dermatology 20150410 2

<h4>Background</h4>Skin needling is a technique used to improve the appearance of acne scarring.<h4>Objective</h4>To comprehensively review the medical literature regarding skin needling as a treatment for acne scarring.<h4>Methods</h4>A literature search was performed using the PubMed, Medline, and Embase databases, in addition to reviewing the bibliographies of relevant articles.<h4>Results</h4>Ten studies presented patients treated with skin needling alone, while eight studies discussed skin ...[more]

PMID: 28491962

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Project description:Hyperparathyroidism-jaw tumor (HPT-JT) syndrome is an autosomal dominant disorder characterized by parathyroid tumors in association with fibro-osseous jaw tumors and uterine and renal lesions. HPT-JT syndrome is caused by germline mutations of the cell division cycle 73 (CDC73) gene that encodes the parafibromin, a 531-amino acid protein with antiproliferative activity. Primary hyperparathyroidism is the main finding of HPT-JT syndrome, usually caused by a single-gland parathyroid involvement (80% of cases), at variance with other variants of hereditary hyperparathyroidism, in which a multiglandular involvement is more frequent. Moreover, parathyroid carcinoma may occur in approximately 20% of cases. Surgery is the treatment of choice for primary hyperparathyroidism, but the extent of surgery remains controversial, varying between bilateral neck and focused exploration, with subtotal or limited parathyroidectomy. Recently, more limited approaches and parathyroid excisions have been suggested in order to decrease the risk of permanent hypoparathyroidism, the main surgical morbidity following more extensive surgical approaches. Ossifying fibromas of the mandible or maxilla may present only in a minority of cases and, even if benign, they should be surgically treated to avoid tumor growth and subsequent functional limitations. Benign and malignant uterine involvement (including leiomyomas, endometrial hyperplasia, adenomyosis, multiple adenomyomatous polyps, and adenosarcomas) is the second most common clinical feature of the syndrome, affecting more than 50% of CDC73-carrier women. Genetic testing should be performed in all family members of affected individuals, in young patients undergoing surgery for primary hyperparathyroidism, or in presence of other associated tumors, allowing early diagnosis and prompt treatment with more tailored surgery. Moreover, CDC73 mutation carriers should be also periodically screened for primary hyperparathyroidism and the other associated tumors. The present review was aimed to summarize the main clinical features of HPT-JT syndrome, focusing on genetic screening and surgical treatment, and to revise the available literature.

Dataset Information

Skin needling as a treatment for acne scarring: An up-to-date review of the literature.

Background

Objective

Methods

Results

Limitations

Conclusion

Publications

Skin needling as a treatment for acne scarring: An up-to-date review of the literature.

Similar Datasets

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