Ontology highlight
ABSTRACT:
SUBMITTER: Man QW
PROVIDER: S-EPMC5420425 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Man Qi-Wen QW Ma Yan-Qi YQ Liu Jin-Yuan JY Zhao Yi Y Liu Bing B Zhao Yi-Fang YF
BioMed research international 20170423
The aim of this study is to clarify whether YAP/TAZ is involved in the pathogenesis and proliferative growth of keratocystic odontogenic tumor (KCOT). The expression levels of YAP/TAZ and downstream proteins and genes in normal oral mucosa (OM) and KCOT were determined and compared by immunohistochemistry and real-time quantitative PCR. The results showed that the expression of YAP/TAZ and downstream proteins (Cyr61, CTGF) was significantly upregulated in KCOT with upregulation of Ki-67 compared ...[more]