Ontology highlight
ABSTRACT:
SUBMITTER: Cao L
PROVIDER: S-EPMC5420558 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Cao Lining L Hu Rui R Xu Ting T Zhang Zhen-Ning ZN Li Weida W Lu Jianfeng J
Frontiers in cellular neuroscience 20170508
In the brain, the serotonergic neurons located in the raphe nucleus are the unique resource of the neurotransmitter serotonin, which plays a pivotal role in the regulation of brain development and functions. Dysfunction of the serotonin system is present in many psychiatric disorders. Lack of <i>in vitro</i> functional human model limits the understanding of human central serotonergic system and its related diseases and clinical applications. Previously, we have developed a method generating hum ...[more]