Ontology highlight
ABSTRACT:
SUBMITTER: Chen J
PROVIDER: S-EPMC5421920 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Chen Junyu J Liu Wanlin W Cao Yuju Y Zhang Xiyang X Guo Yongchang Y Zhu Yong Y Li Jian J Du Jieli J Jin Tianbo T Wang Guoqiang G Wang Jianzhong J
Oncotarget 20170401 15
Our study investigated the association between MMP-3 and MMP-8 single-nucleotide polymorphisms (SNPs) and alcohol-induced osteonecrosis of the femoral head (ONFH) in 695 Chinese males (299 cases and 396 control subjects). The minor allele of MMP-3 rs650108 was associated with a 0.78-fold decrease in alcohol-induced ONFH risk in the allelic model (95% CI = 0.63-0.97, P = 0.026). In the genetic model adjusted for age, rs650108 was associated with decreased risk of alcohol-induced ONFH in the domin ...[more]