Ontology highlight
ABSTRACT:
SUBMITTER: Fischer L
PROVIDER: S-EPMC5423704 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Fischer Lutz L Rappsilber Juri J
Analytical chemistry 20170324 7
Cross-linking/mass spectrometry is an increasingly popular approach to obtain structural information on proteins and their complexes in solution. However, methods for error assessment are under current development. We note that false-discovery rates can be estimated at different points during data analysis, and are most relevant for residue or protein pairs. Missing this point led in our example analysis to an actual 8.4% error when 5% error was targeted. In addition, prefiltering of peptide-spe ...[more]