SS-map: Visualizing cooperative secondary structure elements in protein ensembles.
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ABSTRACT:
SUBMITTER: Iglesias J
PROVIDER: S-EPMC5424797 | biostudies-literature | 2013 Jan-Dec
REPOSITORIES: biostudies-literature
Publications
SS-map: Visualizing cooperative secondary structure elements in protein ensembles.
Iglesias Jelisa J Sanchez-Martínez Melchor M Crehuet Ramon R
Intrinsically disordered proteins 20130101 1
We present SS-map, a tool to visualize the secondary structure content of ensembles of proteins. When generating ensembles of intrinsically disordered proteins, we lose the understanding a single native structure gives for folded proteins. It then becomes difficult to visualize the composition of the ensembles or to detect transient helices such as MoRFs. Conformational propensities for single residues also hide the nature of cooperative structures. Here we show how SS-map describes folded and u ...[more]
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