Ontology highlight
ABSTRACT:
SUBMITTER: Ardiel EL
PROVIDER: S-EPMC5425378 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Ardiel Evan L EL Kumar Abhishek A Marbach Joseph J Christensen Ryan R Gupta Rishi R Duncan William W Daniels Jonathan S JS Stuurman Nico N Colón-Ramos Daniel D Shroff Hari H
Biophysical journal 20170501 9
The lack of physiological recordings from Caenorhabditis elegans embryos stands in stark contrast to the comprehensive anatomical and gene expression datasets already available. Using light-sheet fluorescence microscopy to address the challenges associated with functional imaging at this developmental stage, we recorded calcium dynamics in muscles and neurons and developed analysis strategies to relate activity and movement. In muscles, we found that the initiation of twitching was associated wi ...[more]