Ontology highlight
ABSTRACT:
SUBMITTER: Rona GB
PROVIDER: S-EPMC5425739 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Rona Germana B GB Eleutherio Elis C A ECA Pinheiro Anderson S AS
Biophysical reviews 20160114 1
Chromatin plays an important role in gene transcription control, cell cycle progression, recombination, DNA replication and repair. The fundamental unit of chromatin, the nucleosome, is formed by a DNA duplex wrapped around an octamer of histones. Histones are susceptible to various post-translational modifications, covalent alterations that change the chromatin status. Lysine methylation is one of the major post-translational modifications involved in the regulation of chromatin function. The P ...[more]