Ontology highlight
ABSTRACT:
SUBMITTER: Sun N
PROVIDER: S-EPMC5426085 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Frontiers in microbiology 20170511
The prevalence of multidrug resistance among clinically significant bacteria calls for the urgent development of new antibiotics with novel mechanisms of action. In this study, a new small molecule exhibiting excellent inhibition of bacterial cell division with potent antibacterial activity was discovered through cell-based screening. The compound exhibits a broad spectrum of bactericidal activity, including the methicillin-resistant <i>Staphylococcus aureus</i>, vancomycin-resistant <i>Enteroco ...[more]