Ontology highlight
ABSTRACT:
SUBMITTER: Borkar Y
PROVIDER: S-EPMC5427333 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Borkar Yashvanthi Y Nayak Krishnananda K Shetty Ranjan K RK Bhat Gopalakrishna G Moka Rajasekhar R
Journal of clinical and diagnostic research : JCDR 20170301 3
Gerbode defects are rare Ventricular Septal Defects (VSD) constituting approximately one percent cases of congenital heart diseases. The genetic predispositions towards the Gerbode Defect (GD) have remained an unexplored area of study till date. We investigated the genotype-phenotype correlation in patients with Gerbode VSD. Molecular genetic study on Sanger sequencing and subsequent data analysis showed that the contributing sequence variations in the <i>NKX2-5</i>, <i>GATA4</i> and <i>TBX5</i> ...[more]