Ontology highlight
ABSTRACT:
SUBMITTER: Barnaba C
PROVIDER: S-EPMC5428493 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Barnaba Carlo C Gentry Katherine K Sumangala Nirupama N Ramamoorthy Ayyalusamy A
F1000Research 20170509
Cytochrome P450, a family of monooxygenase enzymes, is organized as a catalytic metabolon, which requires enzymatic partners as well as environmental factors that tune its complex dynamic. P450 and its reducing counterparts-cytochrome P450-reductase and cytochrome <i>b <sub>5</sub></i> -are membrane-bound proteins located in the cytosolic side of the endoplasmic reticulum. They are believed to dynamically associate to form functional complexes. Increasing experimental evidence signifies the role ...[more]