Ontology highlight
ABSTRACT:
SUBMITTER: Yokoyama JS
PROVIDER: S-EPMC5429027 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Yokoyama Jennifer S JS Karch Celeste M CM Fan Chun C CC Bonham Luke W LW Kouri Naomi N Ross Owen A OA Rademakers Rosa R Kim Jungsu J Wang Yunpeng Y Höglinger Günter U GU Müller Ulrich U Ferrari Raffaele R Hardy John J Momeni Parastoo P Sugrue Leo P LP Hess Christopher P CP James Barkovich A A Boxer Adam L AL Seeley William W WW Rabinovici Gil D GD Rosen Howard J HJ Miller Bruce L BL Schmansky Nicholas J NJ Fischl Bruce B Hyman Bradley T BT Dickson Dennis W DW Schellenberg Gerard D GD Andreassen Ole A OA Dale Anders M AM Desikan Rahul S RS
Acta neuropathologica 20170307 5
Corticobasal degeneration (CBD), progressive supranuclear palsy (PSP) and a subset of frontotemporal dementia (FTD) are neurodegenerative disorders characterized by tau inclusions in neurons and glia (tauopathies). Although clinical, pathological and genetic evidence suggests overlapping pathobiology between CBD, PSP, and FTD, the relationship between these disorders is still not well understood. Using summary statistics (odds ratios and p values) from large genome-wide association studies (tota ...[more]