Imputation-Based Whole-Genome Sequence Association Study Rediscovered the Missing QTL for Lumbar Number in Sutai Pigs.
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ABSTRACT:
SUBMITTER: Yan G
PROVIDER: S-EPMC5429657 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Publications
Imputation-Based Whole-Genome Sequence Association Study Rediscovered the Missing QTL for Lumbar Number in Sutai Pigs.
Yan Guorong G Qiao Ruimin R Zhang Feng F Xin Wenshui W Xiao Shijun S Huang Tao T Zhang Zhiyan Z Huang Lusheng L
Scientific reports 20170404 1
Resequencing a number of individuals of various breeds as reference population and imputing the whole-genome sequences of individuals that were genotyped with medium-density chips to perform an association study is a very efficient strategy. Previously, we performed a genome-wide association study (GWAS) of lumbar number using 60K SNPs from the porcine Illumina chips in 418 Sutai pigs and did not detect any significant signals. Therefore, we imputed the whole-genome sequences of 418 Sutai indivi ...[more]
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