Ontology highlight
ABSTRACT:
SUBMITTER: Moldovan RP
PROVIDER: S-EPMC5430395 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
ACS medicinal chemistry letters 20170428 5
Cannabinoid type 2 receptors (CB<sub>2</sub> receptors) are involved in various pathological processes, and the visualization of their <i>in vivo</i> availability with positron emission tomography (PET) is of high interest. The study focuses on the introduction of fluorine into the structure of the highly affine and selective CB<sub>2</sub> receptor ligand <i>N</i>-(adamantan-1-yl)-5-ethyl-2-methyl-1-phenyl-1<i>H</i>-imidazole-4-carboxamide (<b>5</b>). A novel series of compounds was developed b ...[more]