Ontology highlight
ABSTRACT:
SUBMITTER: Tigchelaar S
PROVIDER: S-EPMC5431108 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Tigchelaar Seth S Streijger Femke F Sinha Sunita S Flibotte Stephane S Manouchehri Neda N So Kitty K Shortt Katelyn K Okon Elena E Rizzuto Michael A MA Malenica Ivana I Courtright-Lim Amanda A Eisen Andrew A Keuren-Jensen Kendall Van KV Nislow Corey C Kwon Brian K BK
Scientific reports 20170503 1
Therapeutic development for spinal cord injury is hindered by the difficulty in conducting clinical trials, which to date have relied solely on functional outcome measures for patient enrollment, stratification, and evaluation. Biological biomarkers that accurately classify injury severity and predict neurologic outcome would represent a paradigm shift in the way spinal cord injury clinical trials could be conducted. MicroRNAs have emerged as attractive biomarker candidates due to their stabilit ...[more]