Ontology highlight
ABSTRACT:
SUBMITTER: Mondejar R
PROVIDER: S-EPMC5432176 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Mondejar Rufino R Pérez Cristina C Onaindia Arantza A Martinez Nerea N González-Rincón Julia J Pisonero Helena H Vaqué Jose Pedro JP Cereceda Laura L Santibañez Miguel M Sánchez-Beato Margarita M Piris Miguel Angel MA
PloS one 20170515 5
T and NK-cell lymphoma is a collection of aggressive disorders with unfavorable outcome, in which targeted treatments are still at a preliminary phase. To gain deeper insights into the deregulated mechanisms promoting this disease, we searched a panel of 31 representative T-cell and 2 NK-cell lymphoma/leukemia cell lines for predictive markers of response to targeted therapy. To this end, targeted sequencing was performed alongside the expression of specific biomarkers corresponding to potential ...[more]