The evolution of the major histocompatibility complex in upstream versus downstream river populations of the longnose dace.

ABSTRACT: Populations in upstream versus downstream river locations can be exposed to vastly different environmental and ecological conditions and can thus harbor different genetic resources due to selection and neutral processes. An interesting question is how upstream-downstream directionality in rivers affects the evolution of immune response genes. We used next-generation amplicon sequencing to identify eight alleles of the major histocompatibility complex (MHC) class II β exon 2 in the cyprinid longnose dace (Rhinichthys cataractae) from three rivers in Alberta, upstream and downstream of municipal and agricultural areas along contaminant gradients. We used these data to test for directional and balancing selection on the MHC. We also genotyped microsatellite loci to examine neutral popu

SUBMITTER: Crispo E 

PROVIDER: S-EPMC5433983 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature