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A reconstructed melanoma data set for evaluating differential treatment benefit according to biomarker subgroups.


ABSTRACT: The data presented in this article are related to the research article entitled "Measuring differential treatment benefit across marker specific subgroups: the choice of outcome scale" (Satagopan and Iasonos, 2015) [1]. These data were digitally reconstructed from figures published in Larkin et al. (2015) [2]. This article describes the steps to digitally reconstruct patient-level data on time-to-event outcome and treatment and biomarker groups using published Kaplan-Meier survival curves. The reconstructed data set and the corresponding computer programs are made publicly available to enable further statistical methodology research.

SUBMITTER: Satagopan JM 

PROVIDER: S-EPMC5435579 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature

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A reconstructed melanoma data set for evaluating differential treatment benefit according to biomarker subgroups.

Satagopan Jaya M JM   Iasonos Alexia A   Kanik Joseph G JG  

Data in brief 20170505


The data presented in this article are related to the research article entitled "Measuring differential treatment benefit across marker specific subgroups: the choice of outcome scale" (Satagopan and Iasonos, 2015) [1]. These data were digitally reconstructed from figures published in Larkin et al. (2015) [2]. This article describes the steps to digitally reconstruct patient-level data on time-to-event outcome and treatment and biomarker groups using published Kaplan-Meier survival curves. The r  ...[more]

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