Dataset Information

Presence and extent of cardiac computed tomography angiography defined coronary artery disease in patients presenting with syncope.

ABSTRACT:

Background

In syncope patients, presence of coronary artery disease (CAD) is associated with poor prognosis. However, data concerning CAD prevalence in syncope patients without known cardiovascular disease are lacking. Therefore, the aim of this study was to investigate presence and extent of CAD in syncope patients.

Methods

We included 142 consecutive patients presenting with syncope at the outpatient cardiology clinic who underwent coronary computed tomography (CT) angiography. Syncope type was ascertained by two reviewers, blinded for coronary CT angiography results. Of the patients, 49 had cardiac syncope (arrhythmia or structural cardiopulmonary disease) and 93 had non-cardiac syncope (reflex [neurally-mediated], orthostatic or of unknown cause). Cardiac syncope patients were compared with matched stable chest pain patients regarding age, gender, smoking status, diabetes mellitus type 2 and systolic blood pressure.

Results

Distribution of CAD presence and extent in cardiac and non-cardiac syncope patients was as follows: 72% versus 48% any CAD; 31% versus 26% mild, 8% versus 14% moderate and 33% versus 7% severe CAD. Compared with non-cardiac syncope, patients with cardiac syncope had a significantly higher CAD presence and extent (p = 0.001). Coronary calcium score, segment involvement and stenosis score were also higher in cardiac syncope patients (p-values ?0.004). Compared to the chest pain control group, patients with cardiac syncope showed a higher, however, non-significant, prevalence of any CAD (72% versus 63%) and severe CAD (33% versus 19%).

Conclusion

Patients with cardiac syncope show a high presence and extent of CAD in contrast to non-cardiac syncope patients. These results suggest that CAD may play an important role in the occurrence of cardiac syncope.

SUBMITTER: Altintas S

PROVIDER: S-EPMC5435619 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature

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Presence and extent of cardiac computed tomography angiography defined coronary artery disease in patients presenting with syncope.

Altintas S S Dinh T T Marcks N G H M NGHM Kok M M Aerts A J J AJJ Weijs B B Blaauw Y Y Wildberger J E JE Das M M Kietselaer B L J H BLJH Crijns H J G M HJGM

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20170601 6

<h4>Background</h4>In syncope patients, presence of coronary artery disease (CAD) is associated with poor prognosis. However, data concerning CAD prevalence in syncope patients without known cardiovascular disease are lacking. Therefore, the aim of this study was to investigate presence and extent of CAD in syncope patients.<h4>Methods</h4>We included 142 consecutive patients presenting with syncope at the outpatient cardiology clinic who underwent coronary computed tomography (CT) angiography. ...[more]

PMID: 28321775

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Dataset Information

Presence and extent of cardiac computed tomography angiography defined coronary artery disease in patients presenting with syncope.

Background

Methods

Results

Conclusion

Publications

Presence and extent of cardiac computed tomography angiography defined coronary artery disease in patients presenting with syncope.

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