Ontology highlight
ABSTRACT:
SUBMITTER: Giakoumelou S
PROVIDER: S-EPMC5435679 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Giakoumelou Sevi S Wheelhouse Nick N Brown Jeremy J Wade Jean J Simitsidellis Ioannis I Gibson Douglas D Saunders Philippa T K PTK Horner Patrick P Entrican Gary G Howie Sarah E M SEM Horne Andrew W AW
Scientific reports 20170517 1
Miscarriage affects ~20% of pregnancies and maternal infections account for ~15% of early miscarriages. Chlamydia trachomatis (Ct) has been associated with miscarriage but the underlying mechanisms are unknown. Successful implantation requires endometrial stromal cell (ESC) decidualisation. Maintenance of pregnancy requires angiogenesis, establishment of the correct cellular milieu and trophoblast invasion, all of which involve the action of chemokines. Our objective was to determine whether Ct ...[more]