Ontology highlight
ABSTRACT:
SUBMITTER: Weerts MJA
PROVIDER: S-EPMC5437051 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Weerts Marjolein J A MJA van Marion Ronald R Helmijr Jean C A JCA Beaufort Corine M CM Krol Niels M G NMG Trapman-Jansen Anita M A C AMAC Dinjens Winand N M WNM Sleijfer Stefan S Jansen Maurice P H M MPHM Martens John W M JWM
Scientific reports 20170518 1
The use of blood-circulating cell-free DNA (cfDNA) as 'liquid-biopsy' is explored worldwide, with hopes for its potential in providing prognostic or predictive information in cancer treatment. In exploring cfDNA, valuable repositories are biobanks containing material collected over time, however these retrospective cohorts have restrictive resources. In this study, we aimed to detect tumor-specific mutations in only minute amounts of serum-derived cfDNA by using a targeted next generation sequen ...[more]