Ontology highlight
ABSTRACT:
SUBMITTER: Xu J
PROVIDER: S-EPMC5437288 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Xu Jinshu J Ueno Hiroo H Xu Chelsea Y CY Chen Binglai B Weissman Irving L IL Xu Pin-Xian PX
Nature communications 20170511
The adult mammalian cochlear sensory epithelium houses two major types of cells, mechanosensory hair cells and underlying supporting cells, and lacks regenerative capacity. Recent evidence indicates that a subset of supporting cells can spontaneously regenerate hair cells after ablation only within the first week postparturition. Here in vivo clonal analysis of mouse inner ear cells during development demonstrates clonal relationship between hair and supporting cells in sensory organs. We report ...[more]