Ontology highlight
ABSTRACT:
SUBMITTER: Liu L
PROVIDER: S-EPMC5438676 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Liu Lijun L Li Jingjie J Yan Mengdan M Li Jing J Chen Junyu J Zhang Yi Y Zhu Xikai X Wang Li L Kang Longli L Yuan Dongya D Jin Tianbo T
Oncotarget 20170401 17
Single nucleotide polymorphisms (SNPs) in TCF7L2 (Transcription Factor 7-Like 2) reportedly affect susceptibility to schizophrenia (SCZ). We examined the association between TCF7L2 polymorphisms and SCZ susceptibility in a Chinese Han population. Six SNPs were genotyped in 499 SCZ patients and 500 healthy individuals, after which their associations with SCZ were evaluated using the Chi-squared test and genetic model analyses. We observed that the allele A of rs12573128 is associated with an incr ...[more]