Ontology highlight
ABSTRACT:
SUBMITTER: Xu J
PROVIDER: S-EPMC5438743 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Xu Jianyong J Lian Wei W Li Lingyun L Huang Zhong Z
Oncotarget 20170401 17
It has been demonstrated that cardiac progenitor cells (CPCs) represent a more effective cell-based therapy for treatment of myocardial infarction. Unfortunately, their therapeutic application is limited by low yield of cell harvesting, declining quality and quantity during the ageing process, and the need for highly invasive heart biopsy. Therefore, there is an emerging interest in generating CPC-like stem cells from somatic cells via somatic reprogramming. This novel approach would provide an ...[more]