Ontology highlight
ABSTRACT:
SUBMITTER: Walker VJ
PROVIDER: S-EPMC5439503 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Walker Vyvyca J VJ Agarwal Anupam A
Seminars in nephrology 20160101 1
Iron is an essential metal involved in several major cellular processes required to maintain life. Because of iron's ability to cause oxidative damage, its transport, metabolism, and storage is strictly controlled in the body, especially in the small intestine, liver, and kidney. Iron plays a major role in acute kidney injury and has been a target for therapeutic intervention. However, the therapies that have been effective in animal models of acute kidney injury have not been successful in huma ...[more]