Ontology highlight
ABSTRACT:
SUBMITTER: Smeland OB
PROVIDER: S-EPMC5440373 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Smeland Olav B OB Wang Yunpeng Y Lo Min-Tzu MT Li Wen W Frei Oleksandr O Witoelar Aree A Tesli Martin M Hinds David A DA Tung Joyce Y JY Djurovic Srdjan S Chen Chi-Hua CH Dale Anders M AM Andreassen Ole A OA
Scientific reports 20170522 1
Schizophrenia is associated with differences in personality traits, and recent studies suggest that personality traits and schizophrenia share a genetic basis. Here we aimed to identify specific genetic loci shared between schizophrenia and the Big Five personality traits using a Bayesian statistical framework. Using summary statistics from genome-wide association studies (GWAS) on personality traits in the 23andMe cohort (n = 59,225) and schizophrenia in the Psychiatric Genomics Consortium coho ...[more]