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Transcriptional analysis of genes encoding Shiga toxin 2 and its variants in Escherichia coli.


ABSTRACT: Six of 37 non-O157 Escherichia coli strains possessing Shiga toxin (Stx) 2 gene variant stx(2d) or stx(2e) secreted no detectable Stx. These isolates produced significantly less stx mRNA than Stx2d, Stx2e, Stx2c, or Stx2 secretors did. Standard screening procedures miss a significant subset of E. coli harboring stx(2) variants.

SUBMITTER: Zhang W 

PROVIDER: S-EPMC544208 | biostudies-literature | 2005 Jan

REPOSITORIES: biostudies-literature

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Transcriptional analysis of genes encoding Shiga toxin 2 and its variants in Escherichia coli.

Zhang Wenlan W   Bielaszewska Martina M   Friedrich Alexander W AW   Kuczius Thorsten T   Karch Helge H  

Applied and environmental microbiology 20050101 1


Six of 37 non-O157 Escherichia coli strains possessing Shiga toxin (Stx) 2 gene variant stx(2d) or stx(2e) secreted no detectable Stx. These isolates produced significantly less stx mRNA than Stx2d, Stx2e, Stx2c, or Stx2 secretors did. Standard screening procedures miss a significant subset of E. coli harboring stx(2) variants. ...[more]

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