Bacillus subtilis alpha-phosphoglucomutase is required for normal cell morphology and biofilm formation.
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ABSTRACT:
SUBMITTER: Lazarevic V
PROVIDER: S-EPMC544238 | biostudies-literature | 2005 Jan
REPOSITORIES: biostudies-literature
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Bacillus subtilis alpha-phosphoglucomutase is required for normal cell morphology and biofilm formation.
Lazarevic Vladimir V Soldo Blazenka B Médico Noël N Pooley Harold H Bron Sierd S Karamata Dimitri D
Applied and environmental microbiology 20050101 1
Mutations designated gtaC and gtaE that affect alpha-phosphoglucomutase activity required for interconversion of glucose 6-phosphate and alpha-glucose 1-phosphate were mapped to the Bacillus subtilis pgcA (yhxB) gene. Backcrossing of the two mutations into the 168 reference strain was accompanied by impaired alpha-phosphoglucomutase activity in the soluble cell extract fraction, altered colony and cell morphology, and resistance to phages phi29 and rho11. Altered cell morphology, reversible by a ...[more]
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