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Jupyter and Galaxy: Easing entry barriers into complex data analyses for biomedical researchers.


ABSTRACT: What does it take to convert a heap of sequencing data into a publishable result? First, common tools are employed to reduce primary data (sequencing reads) to a form suitable for further analyses (i.e., the list of variable sites). The subsequent exploratory stage is much more ad hoc and requires the development of custom scripts and pipelines, making it problematic for biomedical researchers. Here, we describe a hybrid platform combining common analysis pathways with the ability to explore data interactively. It aims to fully encompass and simplify the "raw data-to-publication" pathway and make it reproducible.

SUBMITTER: Gruning BA 

PROVIDER: S-EPMC5444614 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature

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Jupyter and Galaxy: Easing entry barriers into complex data analyses for biomedical researchers.

Grüning Björn A BA   Rasche Eric E   Rebolledo-Jaramillo Boris B   Eberhard Carl C   Houwaart Torsten T   Chilton John J   Coraor Nate N   Backofen Rolf R   Taylor James J   Nekrutenko Anton A  

PLoS computational biology 20170525 5


What does it take to convert a heap of sequencing data into a publishable result? First, common tools are employed to reduce primary data (sequencing reads) to a form suitable for further analyses (i.e., the list of variable sites). The subsequent exploratory stage is much more ad hoc and requires the development of custom scripts and pipelines, making it problematic for biomedical researchers. Here, we describe a hybrid platform combining common analysis pathways with the ability to explore dat  ...[more]

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