MetaShot: an accurate workflow for taxon classification of host-associated microbiome from shotgun metagenomic data.
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ABSTRACT:
SUBMITTER: Fosso B
PROVIDER: S-EPMC5447231 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Publications
MetaShot: an accurate workflow for taxon classification of host-associated microbiome from shotgun metagenomic data.
Fosso B B Santamaria M M D'Antonio M M Lovero D D Corrado G G Vizza E E Passaro N N Garbuglia A R AR Capobianchi M R MR Crescenzi M M Valiente G G Pesole G G
Bioinformatics (Oxford, England) 20170601 11
<h4>Summary</h4>Shotgun metagenomics by high-throughput sequencing may allow deep and accurate characterization of host-associated total microbiomes, including bacteria, viruses, protists and fungi. However, the analysis of such sequencing data is still extremely challenging in terms of both overall accuracy and computational efficiency, and current methodologies show substantial variability in misclassification rate and resolution at lower taxonomic ranks or are limited to specific life domains ...[more]
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