Ontology highlight
ABSTRACT:
SUBMITTER: Remark R
PROVIDER: S-EPMC5447326 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Remark Romain R Becker Christian C Gomez Jorge E JE Damotte Diane D Dieu-Nosjean Marie-Caroline MC Sautès-Fridman Catherine C Fridman Wolf-Herman WH Powell Charles A CA Altorki Nasser K NK Merad Miriam M Gnjatic Sacha S
American journal of respiratory and critical care medicine 20150201 4
Solid tumors, beyond mere accumulation of cancer cells, form a complex ecosystem consisting of normal epithelial cells, fibroblasts, blood and lymphatic vessels, structural components, and infiltrating hematopoietic cells including myeloid and lymphoid elements that impact tumor growth, tumor spreading, and clinical outcome. The composition of the immune microenvironment is diverse, including various populations of T cells, B cells, dendritic cells, natural killer cells, myeloid-derived suppress ...[more]