Ontology highlight
ABSTRACT:
SUBMITTER: Neme R
PROVIDER: S-EPMC5447804 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Neme Rafik R Amador Cristina C Yildirim Burcin B McConnell Ellen E Tautz Diethard D
Nature ecology & evolution 20170424 6
It is generally assumed that new genes arise through duplication and/or recombination of existing genes. The probability that a new functional gene could arise out of random non-coding DNA is so far considered to be negligible, since it seems unlikely that such a RNA or protein sequence could have an initial function that influences the fitness of an organism. We have here tested this question systematically, by expressing clones with random sequences in <i>E . coli</i> and subjecting them to co ...[more]