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An outbreak of duck hepatitis A virus type 1 infection in Japan.


ABSTRACT: In June 2015, a highly fatal and acute disease broke out in a duckling farm in Hyogo Prefecture, Japan. The birds exhibited poor growth, reduced movement, lying in a dorsal recumbent position, depression, lethargy, ataxia and opisthotonus, with a high mortality rate of approximately 76%. By performing a reverse transcription-polymerase chain reaction (RT-PCR) using primers specific for duck hepatitis A virus type 1 (DHAV-1), we obtained the PCR products of a predicted size. The nucleotide sequences of the PCR products showed a >96% identity with that of the DHAV-1, HB02 strain, which was isolated in China. To our knowledge, this is the first time that the DHAV-1 virus has been isolated since its outbreak in Japan in 1963.

SUBMITTER: Kamomae M 

PROVIDER: S-EPMC5447982 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature

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An outbreak of duck hepatitis A virus type 1 infection in Japan.

Kamomae Masahiro M   Kameyama Mamoru M   Ishii Jun J   Nabe Mikoto M   Ogura Yuji Y   Iseki Hiroshi H   Yamamoto Yu Y   Mase Masaji M  

The Journal of veterinary medical science 20170411 5


In June 2015, a highly fatal and acute disease broke out in a duckling farm in Hyogo Prefecture, Japan. The birds exhibited poor growth, reduced movement, lying in a dorsal recumbent position, depression, lethargy, ataxia and opisthotonus, with a high mortality rate of approximately 76%. By performing a reverse transcription-polymerase chain reaction (RT-PCR) using primers specific for duck hepatitis A virus type 1 (DHAV-1), we obtained the PCR products of a predicted size. The nucleotide sequen  ...[more]

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