Ontology highlight
ABSTRACT:
SUBMITTER: Kim A
PROVIDER: S-EPMC5448069 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Kim AeRang A Stewart Douglas R DR Reilly Karlyne M KM Viskochil David D Miettinen Markku M MM Widemann Brigitte C BC
Sarcoma 20170516
Malignant peripheral nerve sheath tumor (MPNST) is the leading cause of mortality in patients with neurofibromatosis type 1. In 2002, an MPNST consensus statement reviewed the current knowledge and provided guidance for the diagnosis and management of MPNST. Although the improvement in clinical outcome has not changed, substantial progress has been made in understanding the natural history and biology of MPNST through imaging and genomic advances since 2002. Genetically engineered mouse models t ...[more]