Ontology highlight
ABSTRACT:
SUBMITTER: Chen YT
PROVIDER: S-EPMC5449628 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Chen Yu-Ting YT Chang Kai-Chun KC Hu Hao-Teng HT Chen Yi-Lan YL Lin You-Hsin YH Hsu Chiung-Fang CF Chang Cheng-Fu CF Chang Kung-Yao KY Wen Jin-Der JD
Nucleic acids research 20170601 10
Frameshifting is an essential process that regulates protein synthesis in many viruses. The ribosome may slip backward when encountering a frameshift motif on the messenger RNA, which usually contains a pseudoknot structure involving tertiary base pair interactions. Due to the lack of detailed molecular explanations, previous studies investigating which features of the pseudoknot are important to stimulate frameshifting have presented diverse conclusions. Here we constructed a bimolecular pseudo ...[more]