Ontology highlight
ABSTRACT:
SUBMITTER: Chitale S
PROVIDER: S-EPMC5449631 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Chitale Shalaka S Richly Holger H
Nucleic acids research 20170601 10
Repair of damaged DNA relies on the recruitment of DNA repair factors in a well orchestrated manner. As a prerequisite, the chromatin needs to be decondensed by chromatin remodelers to allow for binding of repair factors and for DNA repair to occur. Recent studies have implicated members of the SWI/SNF and INO80 families as well as PARP1 in nucleotide excision repair (NER). In this study, we report that the endonuclease DICER is implicated in chromatin decondensation during NER. In response to U ...[more]