Differential Protein Expressions in Virus-Infected and Uninfected Trichomonas vaginalis.

ABSTRACT: Protozoan viruses may influence the function and pathogenicity of the protozoa. Trichomonas vaginalis is a parasitic protozoan that could contain a double stranded RNA (dsRNA) virus, T. vaginalis virus (TVV). However, there are few reports on the properties of the virus. To further determine variations in protein expression of T. vaginalis, we detected 2 strains of T. vaginalis; the virus-infected (V⁺) and uninfected (V^-) isolates to examine differentially expressed proteins upon TVV infection. Using a stable isotope N-terminal labeling strategy (iTRAQ) on soluble fractions to analyze proteomes, we identified 293 proteins, of which 50 were altered in V⁺ compared with V^- isolates. The results showed that the expression

SUBMITTER: He D 

PROVIDER: S-EPMC5450954 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature