Ontology highlight
ABSTRACT:
SUBMITTER: Du Y
PROVIDER: S-EPMC5453462 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Du Yang Y Deng Wenjun W Wang Zixing Z Ning MingMing M Zhang Wei W Zhou Yiming Y Lo Eng H EH Xing Changhong C
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20160101 4
Mice and rats are the most commonly used animals for preclinical stroke studies, but it is unclear whether targets and mechanisms are always the same across different species. Here, we mapped the baseline expression of a chemokine/cytokine subnetwork and compared responses after oxygen-glucose deprivation in primary neurons, astrocytes, and microglia from mouse, rat, and human. Baseline profiles of chemokines (CX3CL1, CXCL12, CCL2, CCL3, and CXCL10) and cytokines (IL-1α, IL-1β, IL-6, IL-10, and ...[more]