Ontology highlight
ABSTRACT:
SUBMITTER: Baillie R
PROVIDER: S-EPMC5454033 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Baillie Ranui R Tan Swee T ST Itinteang Tinte T
Frontiers in oncology 20170602
Cancer stem cells (CSCs) have been identified in oral cavity squamous cell carcinoma (OCSCC). CSCs possess the ability for perpetual self-renewal and proliferation, producing downstream progenitor cells and cancer cells that drive tumor growth. Studies of many cancer types including OCSCC have identified CSCs using specific markers, but it is still unclear as to where in the stem cell hierarchy these markers fall. This is compounded further by the presence of multiple CSC subtypes within OCSCC, ...[more]