Dataset Information

A Syst-OMICS Approach to Ensuring Food Safety and Reducing the Economic Burden of Salmonellosis.

ABSTRACT: The Salmonella Syst-OMICS consortium is sequencing 4,500 Salmonella genomes and building an analysis pipeline for the study of Salmonella genome evolution, antibiotic resistance and virulence genes. Metadata, including phenotypic as well as genomic data, for isolates of the collection are provided through the Salmonella Foodborne Syst-OMICS database (SalFoS), at https://salfos.ibis.ulaval.ca/. Here, we present our strategy and the analysis of the first 3,377 genomes. Our data will be used to draw potential links between strains found in fresh produce, humans, animals and the environment. The ultimate goals are to understand how Salmonella evolves over time, improve the accuracy of diagnostic methods, develop control methods in the field, and identify prognostic markers for evidence-based decisions in epidemiology and surveillance.

SUBMITTER: Emond-Rheault JG

PROVIDER: S-EPMC5454079 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature

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Publications

A Syst-OMICS Approach to Ensuring Food Safety and Reducing the Economic Burden of Salmonellosis.

Emond-Rheault Jean-Guillaume JG Jeukens Julie J Freschi Luca L Kukavica-Ibrulj Irena I Boyle Brian B Dupont Marie-Josée MJ Colavecchio Anna A Barrere Virginie V Cadieux Brigitte B Arya Gitanjali G Bekal Sadjia S Berry Chrystal C Burnett Elton E Cavestri Camille C Chapin Travis K TK Crouse Alanna A Daigle France F Danyluk Michelle D MD Delaquis Pascal P Dewar Ken K Doualla-Bell Florence F Fliss Ismail I Fong Karen K Fournier Eric E Franz Eelco E Garduno Rafael R Gill Alexander A Gruenheid Samantha S Harris Linda L Huang Carol B CB Huang Hongsheng H Johnson Roger R Joly Yann Y Kerhoas Maud M Kong Nguyet N Lapointe Gisèle G Larivière Line L Loignon Stéphanie S Malo Danielle D Moineau Sylvain S Mottawea Walid W Mukhopadhyay Kakali K Nadon Céline C Nash John J Ngueng Feze Ida I Ogunremi Dele D Perets Ann A Pilar Ana V AV Reimer Aleisha R AR Robertson James J Rohde John J Sanderson Kenneth E KE Song Lingqiao L Stephan Roger R Tamber Sandeep S Thomassin Paul P Tremblay Denise D Usongo Valentine V Vincent Caroline C Wang Siyun S Weadge Joel T JT Wiedmann Martin M Wijnands Lucas L Wilson Emily D ED Wittum Thomas T Yoshida Catherine C Youfsi Khadija K Zhu Lei L Weimer Bart C BC Goodridge Lawrence L Levesque Roger C RC

Frontiers in microbiology 20170602

The Salmonella Syst-OMICS consortium is sequencing 4,500 Salmonella genomes and building an analysis pipeline for the study of Salmonella genome evolution, antibiotic resistance and virulence genes. Metadata, including phenotypic as well as genomic data, for isolates of the collection are provided through the Salmonella Foodborne Syst-OMICS database (SalFoS), at https://salfos.ibis.ulaval.ca/. Here, we present our strategy and the analysis of the first 3,377 genomes. ...[more]

PMID: 28626454

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Project description:BACKGROUND:In the United States, patients who have breast cancer experience significant economic burden compared with those who have other types of cancers. Cancer-related economic burden is exacerbated by adverse treatment effects. Strategies to resolve the economic burden caused by breast cancer and its adverse treatment effects have stemmed from the perspectives of health care providers, oncology navigators, and other subject-matter experts. For the current study, patient-driven recommendations were elicited to reduce economic burden after 1) breast cancer and 2) breast cancer-related lymphedema, which is a common, persistent adverse effect of breast cancer. METHODS:Qualitative interviews were conducted with 40 long-term breast cancer survivors who were residents of Pennsylvania or New Jersey in 2015 and were enrolled in a 6-month observational study. Purposive sampling ensured equal representation by age, socioeconomic position, and lymphedema diagnosis. Semistructured interviews addressed economic challenges, supports used, and patient recommendations for reducing financial challenges. Interviews were coded, and representative quotes from the patient recommendations were analyzed and reported to illustrate key findings. RESULTS:Of 40 interviewees (mean age, 64 years; mean time since diagnosis, 12 years), 27 offered recommendations to reduce the economic burden caused by cancer and its adverse treatment effects. Nine recommendations emerged across 4 major themes: expanding affordable insurance and insurance-covered items, especially for lymphedema treatment (among the 60% who reported lymphedema); supportive domestic help; financial assistance from diagnosis through treatment; and employment-preserving policies. CONCLUSIONS:The current study yielded 9 actionable, patient-driven recommendations-changes to insurance, supportive services, financial assistance, and protective policies-to reduce breast cancer-related economic burden. These recommendations should be tested through policy and programmatic interventions.

Dataset Information

A Syst-OMICS Approach to Ensuring Food Safety and Reducing the Economic Burden of Salmonellosis.

Publications

A Syst-OMICS Approach to Ensuring Food Safety and Reducing the Economic Burden of Salmonellosis.

Similar Datasets

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