Ontology highlight
ABSTRACT:
SUBMITTER: Vardar G
PROVIDER: S-EPMC545643 | biostudies-literature | 2005 Feb
REPOSITORIES: biostudies-literature
Vardar Gönül G Wood Thomas K TK
Journal of bacteriology 20050201 4
Alpha-subunit position M180 of toluene-o-xylene monooxygenase influences the regiospecific oxidation of aromatics (e.g., from o-cresol, M180H forms 3-methylcatechol, methylhydroquinone, and 4-methylresorcinol, whereas the wild type forms only 3-methylcatechol). Position E214 influences the rate of reaction (e.g., E214G increases p-nitrophenol oxidation 15-fold) by controlling substrate entrance and product efflux as a gate residue. ...[more]