Inactivated Sendai Virus (HVJ-E) Immobilized Electrospun Nanofiber for Cancer Therapy.
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ABSTRACT:
SUBMITTER: Okada T
PROVIDER: S-EPMC5456544 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
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Inactivated Sendai Virus (HVJ-E) Immobilized Electrospun Nanofiber for Cancer Therapy.
Okada Takaharu T Niiyama Eri E Uto Koichiro K Aoyagi Takao T Ebara Mitsuhiro M
Materials (Basel, Switzerland) 20151226 1
Inactivated Hemagglutinating Virus of Japan Envelope (HVJ-E) was immobilized on electrospun nanofibers of poly(<i>ε</i>-caprolactone) by layer-by-layer (LbL) assembly technique. The precursor LbL film was first constructed with poly-L-lysine and alginic acid via electrostatic interaction. Then the HVJ-E particles were immobilized on the cationic PLL outermost surface. The HVJ-E adsorption was confirmed by surface wettability test, scanning laser microscopy, scanning electron microscopy, and conf ...[more]
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