Ontology highlight
ABSTRACT:
SUBMITTER: Gonzalez E
PROVIDER: S-EPMC5456551 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
González Edurne E Shepherd Larissa M LM Saunders Laura L Frey Margaret W MW
Materials (Basel, Switzerland) 20160114 1
In this work, biotin surface functionalized hydrophilic non-water-soluble biocompatible poly(lactic acid) (PLA) nanofibers are created for their potential use as biosensors. Varying concentrations of biotin (up to 18 weight total percent (wt %)) were incorporated into PLA fibers together with poly(lactic acid)-block-poly(ethylene glycol) (PLA-<i>b</i>-PEG) block polymers. While biotin provided surface functionalization, PLA-<i>b</i>-PEG provided hydrophilicity to the final fibers. Morphology and ...[more]