Ontology highlight
ABSTRACT:
SUBMITTER: Cheng Z
PROVIDER: S-EPMC5458197 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Cheng Zhenguo Z Liu Funan F Zhang Hongyan H Li Xiaodong X Li Yanshu Y Li Jiabin J Liu Furong F Cao Yu Y Cao Liu L Li Feng F
Oncotarget 20170501 19
Tumor metastasis has been the major cause of recurrence and death in patients with gastric cancer. Here, we find miR-135a has a decreased expression in the metastatic cell lines compared with its parental cell lines by analyzing microRNA array. Further results show that miR-135a is downregulated in the majority of human gastric cancer tissues and cell lines. Decreased expression of miR-135a is associated with TNM stage and poor survival. Besides, regaining miR-135a in gastric cancer cells obviou ...[more]