Ontology highlight
ABSTRACT:
SUBMITTER: Perilla JR
PROVIDER: S-EPMC5459578 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Perilla Juan R JR Zhao Gongpu G Lu Manman M Ning Jiying J Hou Guangjin G Byeon In-Ja L IL Gronenborn Angela M AM Polenova Tatyana T Zhang Peijun P
The journal of physical chemistry. B 20170222 15
Single particle cryoEM has emerged as a powerful method for structure determination of proteins and complexes, complementing X-ray crystallography and NMR spectroscopy. Yet, for many systems, the resolution of cryoEM density map has been limited to 4-6 Å, which only allows for resolving bulky amino acids side chains, thus hindering accurate model building from the density map. On the other hand, experimental chemical shifts (CS) from solution and solid state MAS NMR spectra provide atomic level ...[more]