Ontology highlight
ABSTRACT:
SUBMITTER: Clausen MV
PROVIDER: S-EPMC5459889 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Clausen Michael V MV Hilbers Florian F Poulsen Hanne H
Frontiers in physiology 20170606
The sodium and potassium gradients across the plasma membrane are used by animal cells for numerous processes, and the range of demands requires that the responsible ion pump, the Na,K-ATPase, can be fine-tuned to the different cellular needs. Therefore, several isoforms are expressed of each of the three subunits that make a Na,K-ATPase, the alpha, beta and FXYD subunits. This review summarizes the various roles and expression patterns of the Na,K-ATPase subunit isoforms and maps the sequence v ...[more]